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Head of Informatics (Cheminformatics)

Sci.bio Recruiting

New York, United States

An emerging biotech company at the intersection of artificial intelligence, medicinal chemistry, and automation is seeking a Director of Scientific Informatics to build and lead the scientific data ecosystem powering next-generation drug discovery.

This is a highly visible, hands-on leadership opportunity for someone excited by the challenge of integrating chemistry, biology, laboratory automation, and machine learning into a unified scientific platform. The successful candidate will help shape how data moves from the bench to predictive models and ultimately influences discovery decisions.

Responsibilities

  • Own and administer core scientific informatics platforms supporting chemistry and biology workflows
  • Lead integrations across ELN/LIMS, registration systems, inventory platforms, laboratory automation, cloud infrastructure, and downstream analytics
  • Partner closely with biology, chemistry, automation, and machine learning teams to ensure scientific data is structured, curated, and accessible
  • Establish data standards, metadata conventions, and governance practices across chemistry and biology datasets
  • Improve assay data capture, analysis, reporting, and transfer workflows while reducing manual processes
  • Serve as the primary point of contact for informatics vendors and external partners
  • Develop SOPs and best practices for scientific data management
  • Mentor and help grow informatics and data engineering capabilities as the organization scales

Qualifications

  • BS, MS, or PhD in Chemistry, Biology, Bioinformatics, Computer Science, or related discipline
  • 10+ years of experience in scientific informatics, cheminformatics, or research informatics within biotech or pharmaceutical environments
  • Hands-on experience with scientific platforms such as ELNs, LIMS, registration systems, assay data systems, or laboratory automation platforms
  • Strong understanding of medicinal chemistry and biology workflows, including SAR analysis, DMTA cycles, and multiparameter optimization
  • Experience building scientific data pipelines and implementing metadata harmonization and governance strategies
  • Proven ability to work cross-functionally with Biology, Chemistry, Automation, Data Science, and Machine Learning teams
  • Proficiency in Python and SQL
  • Strong communication skills with the ability to balance strategic planning and hands-on execution

Preferred Experience

  • Integrating predictive modeling and machine learning into discovery workflows
  • Experience with cheminformatics toolkits such as RDKit or related technologies
  • Familiarity with workflow and visualization platforms such as KNIME, Pipeline Pilot, or Spotfire
  • Experience with AWS, Docker, REST APIs, and modern scientific data engineering practices
  • Knowledge of active learning, Bayesian optimization, or ML-driven compound design
  • Prior experience in startup or growth-stage biotech environments
Apply on linkedin

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